Mepiform® clinical references
- Efficacy of a soft silicone sheet on hypertrophic scars: Both regimens were associated with a significant reduction in the clinical signs of hypertrophic scars over 12 weeks of treatment. The polyurethane dressing demonstrated a significantly more pronounced reduction in severity of these clinical signs after four and eight weeks of treatment and was better tolerated than the silicone sheet.
- Evaluation of a self-adherent soft silicone dressing for the treatment of hypertrophic postoperative scars: The results suggest that patients treated with the soft silicone dressing experienced greater and more rapid improvements compared with non-treated patients. These results concur with those of previous studies. The fact that Mepiform is self-adhesive and causes limited damage to the stratum corneum on removal gives it an added value compared with non-adhesive silicone gel dressings.
- A Randomized, Single-Blind Trial of Clobetasol Propionate 0.05% Cream Under Silicone Dressing Occlusion Versus Intra-Lesional Triamcinolone for Treatment of Keloid: Silicone dressing is equally effective and has fewer adverse effects compared to IL triamcinolone. Hence, it may be used as an alternative treatment for keloid particularly in patients with low pain threshold, needle phobia and those who prefers home-based treatment.
- The use of pressure and silicone in hypertrophic scar management in burns patients: a pilot randomized controlled trial.
- Silicone: It is recommended that patients wear silicone sheets for 12–24 hours per day for 3–6 months. Silicone gels should be applied twice daily.